| 谷氨酰胺诱导热休克蛋白对急性肺损伤的保护作用 |
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| 引用本文： | 梁梦凡,王学敏,江伟. 谷氨酰胺诱导热休克蛋白对急性肺损伤的保护作用[J]. 上海交通大学学报(医学版), 2007, 27(1): 114-116 |
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| 作者姓名： | 梁梦凡 王学敏 江伟 |
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| 作者单位： | 上海交通大学,第六人民医院麻醉科,上海,200233;上海交通大学,第六人民医院麻醉科,上海,200233;上海交通大学,第六人民医院麻醉科,上海,200233 |
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| 摘 要： | 热休克蛋白的表达对急性肺损伤(ALI)有保护作用,而以往的诱导药物大多有毒有害,限制了其临床应用。谷氨酰胺能够诱导热休克蛋白表达,对ALI和脓毒症产生保护作用,具有潜在的临床应用价值。
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| 关 键 词： | 热休克蛋白 急性肺损伤 谷氨酰胺 |
| 文章编号： | 0258-5898（2007）01-0114-03 |
| 修稿时间： | 2006-03-02 |
Glutamine induces heat shock proteins to protect against acute lung injury |
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| LIANG Meng-fan,WANG Xue-min,JIANG Wei. Glutamine induces heat shock proteins to protect against acute lung injury[J]. Journal of Shanghai Jiaotong University:Medical Science, 2007, 27(1): 114-116 |
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| Authors: | LIANG Meng-fan WANG Xue-min JIANG Wei |
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| Abstract: | The expression of heat shock proteins(HSPs) can protect against acute lung injury(ALI).However,HSPs are restrained from clinical application due to the toxicity of most of the former inductors.Glutamine,which also has the ability to induce the expression of HSPs,can protect against ALI and sepsis,and may serve as a candidate for clinical application. |
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| Keywords: | heat shock proteins acute lung injury glutamine |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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