Presence of quinolone resistance to qnrB1 genes and blaOXA-48 carbapenemase in clinical isolates of Klebsiella pneumoniae in Spain |
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| Authors: | J.M. Rodrí guez Martí nez,P. Dí az-de Alba,Lopez-Cerero,G. Ruiz-Carrascoso,R. Gomez-Gil,A. Pascual |
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| Affiliation: | 1. Departamento de Microbiología, Universidad de Sevilla, Sevilla, Spain;2. Servicio de Microbiología, Hospital Universitario La Paz, Madrid, Spain;3. Unidad de Enfermedades Infeccionas y Microbiología Clínica, Hospital Universitario Virgen Macarena, Sevilla, Spain |
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| Abstract: | ![]()
A study is presented on the presence of quinolone resistance qnrB1 genes in clinical isolates belonging to the largest series of infections caused by OXA-48-producing Klebsiella pneumoniae in a single-centre outbreak in Spain. Evidence is also provided, according to in vitro results, that there is a possibility of co-transfer of plasmid harbouring blaOXA-48 with an other plasmid harbouring qnrB1 in presence of low antibiotic concentrations of fluoroquinolones, showing the risk of multi-resistance screening. |
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| Keywords: | PMQR qnr Carbapenems blaOXA-48 |
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