Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next‐generation sequencing with a 25‐gene panel期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next‐generation sequencing with a 25‐gene panel

Authors:	Brian Allen MS Rajesh Kaldate MS Satish Bhatnagar PhD Karla Bowles PhD Kirsten Timms PhD Judy E. Garber MD Christina Herold MD Leif Ellisen MD PhD Jill Krejdovsky MS Kim DeLeonardis MS Kristin Sedgwick MS Kathleen Soltis MA Benjamin Roa PhD Richard J. Wenstrup MD Anne‐Renee Hartman MD

Affiliation:	1. Clinical Affairs, Myriad Genetic Laboratories, Inc., Salt Lake City, Utah;2. Technical and Product Development, Myriad Genetics, Inc., Salt Lake City, Utah;3. Diagnostic Development, Myriad Genetic Laboratories, Inc., Salt Lake City, Utah;4. Research, Myriad Genetics, Inc., Salt Lake City, Utah;5. Department of Medicine, Harvard Medical School, Boston, Massachusetts;6. Division of Population Sciences and Adult OncologyDana‐Farber Cancer Institute;7. Division of Hematology‐Oncology, Beth Israel Deaconess Medical Center, Boston, Massachusetts;8. Department of Hematology/Oncology and MedicineMassachusetts General Hospital;9. Cancer Genetics and Prevention Program, Beth Israel Deaconess Medical Center, Boston, MA;10. Medical Services, Myriad Genetic Laboratories, Inc., Salt Lake City, Utah

Abstract:

Keywords:	high‐throughput nucleotide sequencing breast neoplasms genetic testing BRCA1 BRCA2