高频彩超联合MRI在乳腺癌早期诊断及分期中的应用

目的分析高频彩超联合磁共振成像(Magnetic Resonance Imaging,MRI)在乳腺癌早期诊断及分期中的应用价值。方法选取2017年1月-2018年2月我院收治的90例病理证实早期乳腺癌患者作为研究对象,均行高频彩超、MRI检查,对病灶进行分期,以术后病理学结果为"金标准",比较单纯采用高频彩超、MRI及联合检查准确性。结果联合检查正确率97.78%,明显高于单纯采用高频彩超检查82.22%与单纯采用MRI检查92.22%(P<0.05);高频彩超联合MRI检查乳腺癌T1灵敏度为95.24%(20/21),特异度100.00%(69/69),准确性98.89%(89/90),K a p p a值为0. 9 7;检查T2灵敏度为100.00%(32/32),特异度98.28%(57/58),准确性98.89%(89/90),Kappa值为0.98;检查T3灵敏度为96.43%(27/28),特异度100.00%(62/62),准确性98.89%(89/90),K a p p a值为0. 9 7;检查T4灵敏度为88.89%(8/9),特异度97.53%(79/81),准确性96.67%(87/90),Kappa值为0.82;高频彩超联合MRI检查乳腺癌T1、T2、T3、T4灵敏度、特异度、准确性均高于单纯采用高频彩超与MRI检查。结论高频彩超联合MRI能够提高乳腺癌早期诊断及分期准确性,为患者临床诊治提供有效指导。

Application of High-frequency Color Doppler Ultrasound Combined with MRI in Early Diagnosis and Staging of Breast Cancer

Objective To analyze the application of high-frequency color Doppler ultrasound combined with magnetic resonance imaging(MRI) in the early diagnosis and staging of breast cancer. Methods 90 cases of patients pathologically confirmed with earlystage breast cancer who were admitted to our hospital from January 2017 to February 2018 were selected for the study and were given high-frequency color Doppler ultrasound and MRI. The lesions were staged and the postoperative pathological findings were taken as gold standard, and the accuracy rates of high-frequency color Doppler ultrasound, MRI and combined examination were compared. Results The accuracy rate of combined examination was significantly higher than that of single high-frequency color Doppler ultrasound and single MRI(97.78% vs 82.22% vs 92.22%)(P<0.05). The sensitivity, specificity, accuracy and Kappa value were 95.24%(20/21), 100.00%(69/69), 98.89%(89/90) and 0.97 by high-frequency color ultrasound combined with MRI in diagnosing breast cancer T1, and were 100.00%(32/32), 98.28%(57/58), 98.89%(89/90) and 0.98 in T2, and were 96.43%(27/28), 100.00%(62/62), 98.89%(89/90) and 0.97 in T3, and were 88.89%(8/9), 97.53%(79/81), 96.67%(87/90) and 0.82 in T4. The sensitivity, specificity and accuracy of high-frequency color Doppler ultrasound combined with MRI in detecting breast cancer T1, T2, T3 and T4 were higher than those of single high-frequency color Doppler ultrasound or single MRI. Conclusion High-frequency color Doppler ultrasound combined with MRI can improve the early diagnosis and staging accuracy of breast cancer, and provide effective guidance for clinical diagnosis and treatment of patients.