| 光疗前后新生儿的DNA指纹分析 |
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| 引用本文： | 王黛,王家锦,辛德丽,张小为,史秀芬,穆莹.光疗前后新生儿的DNA指纹分析[J].北京大学学报(医学版),1996(4). |
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| 作者姓名： | 王黛 王家锦 辛德丽 张小为 史秀芬 穆莹 |
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| 作者单位： | 北京医科大学人民医院医学遗传科，北京市友谊医院儿科，北京市刑事科学技术研究所 |
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| 摘 要： | 目的：了解光疗对新生儿的ＤＮＡ是否有损伤。方法：采用ＬＥ１１．８小卫星探针，经Ｓｏｕｔｈｅｒｎ印迹法检测接受光疗前后新生儿外周血的ＤＮＡ指纹谱带。结果：２２例接受光疗前后的新生儿ＤＮＡ指纹相比，均未见到任何谱带的改变。结论：光疗未引起新生儿的ＤＮＡ损伤，应用国产蓝光治疗器对高胆红素血症新生儿在４８ｈ内治疗是安全的。
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| 关 键 词： | 光疗法，DNA指纹图谱，DNA损伤 |
DNA FINGERPRINTS ANALYSIS OF NEWBORNS TRkATED BY PHOTOTHERAPY |
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| WANG Dai,WANG Jiajin,XIN Deli,ZNANG Xiaowei,SHI Xiufen,MU Ying.DNA FINGERPRINTS ANALYSIS OF NEWBORNS TRkATED BY PHOTOTHERAPY[J].Journal of Peking University:Health Sciences,1996(4). |
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| Authors: | WANG Dai WANG Jiajin XIN Deli ZNANG Xiaowei SHI Xiufen MU Ying |
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| Abstract: | Objective:To investigate whether there is DNA damage of infants treated by phototherapy.Methods:Detection of DNA Fingerprints of the infants by Southern blot hybridization using LE 11.8 probe,Results:No bands change of DNA Fingerprints of 22 infants treated before and during pho-totherapy.Conclusion:No DNA damage was seen in the infants treated by phototherapy. It is safe for infants to be treated by phototherapy within 48 hours. |
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| Keywords: | Headings Phototherapy DNA fingerprinting DNA darnage |
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