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Discovery of Benzimidazole Oxazolidinediones as Novel and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists
Authors:Christine Yang  Jaume Balsells  Hong D. Chu  Jason M. Cox  Alejandro Crespo  Xiuying Ma  Lisa Contino  Patricia Brown  Sheng Gao  Beata Zamlynny  Judyann Wiltsie  Joseph Clemas  JeanMarie Lisnock  Jack Gibson  Gaochao Zhou  Margarita Garcia-Calvo  Thomas J. Bateman  Vincent Tong  Ling Xu  Martin Crook  Peter Sinclair  Hong C. Shen
Affiliation:Merck Research Laboratories, Merck &Co., Kenilworth, New Jersey 07033, United States
Abstract:
Keywords:mineralocorticoid receptor   antagonist   amidereplacement   oxazolidinedione   natriuresis effect
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