T细胞在动脉粥样硬化中的作用

T细胞作为一种炎性细胞,在动脉粥样硬化的形成以及斑块的活动中起到了关键作用。T细胞表面潜在的抗原抗体所激活的信号通路,使不同的T细胞亚群具有促炎或抗炎的特性。激活的T细胞与血管壁周围其他细胞存在的细胞间的相互作用,T细胞表面的共刺激分子存在的分子间的相互作用,从新的角度揭示了动脉粥样硬化形成的复杂过程。

The Role of T Cells in Atherosclerosis

As inflammatory cells,T cells get involved and play a critical role in pathogenesy and development of atherosclerosis.The potential antigen or antibodies expressed in T cells induce the signal path way,promoting the inflammatory or anti-inflammatory of different T cell subsets.The mutual effect between activation T cells and other cells surrounding the vessel wall,as well as the intermolecular interaction between costimulatory molecules expressed in T cells are co-regulating the complex process of atherosclerosis formation in the new point of view.