1056例肺结核患者耐药性分析

目的 调查目前肺结核患者耐药情况.方法 对我院1056例肺结核患者耐药情况进行调查.结果 1056例肺结核患者,经痰结核菌培养阳性474例,进行药敏试验304例,耐药肺结核患者111例,原发性耐药34例,耐药率18.6％,获得性耐药77例,耐药率68.1％,原发性、获得性单耐药、耐多药、多耐药经统计学分析,也存在显著差异性(P＜o.05).结论 在现行的DOTS策略下,仍然存在耐药患者甚至耐多药患者,对于这部分治疗失败的患者,尽早药敏试验,根据药敏结果,个体化治疗,控制传染源.

Analysis of drug resistance in 1056 cases of pulmonary tuberculosis

Objective To invesgate current drug resistance of TB.Methods Drug resistance of 1056 cases with pulmonary tuberculosis in our hospital was observed.Results In 1056 pulmonary tuberculosis patient,sputum culture positive with 474 cases,drug sensitive test positive with 304 cases,drug resistant pulmonary tuberculosis with 111 cases,primary drug-resistance with 34 cases,and the rate of drug resistance was 18.6%;acquired drug-resistance with 77 cases,and the rate of drug resistance was 68.1%;primary drug-resistance,acquired drug-resistance,and multidrug-resistance were statistically analysed,there were significant differences(P<0.005).Conclusion Under the present DOTS strategy,patients of drug resistance,and even the patient of multidrug-resistance,still exist.For the patients of treatment failure,drug sensitive test should made,and according to its results,we can take individul treatment and control the origin of infection.