三维超声对非溃疡性消化不良患者胃排空功能的初步研究

目的 探讨三维超声对服用疏肝和胃冲剂的非溃疡性消化不良(NUD)患者胃排空功能的诊断价值.方法 60例NUD患者随机分为疏肝和胃冲剂治疗组(中药组)和吗丁啉治疗组(西药组)各30例,应用三维超声技术测量胃排空时间和胃窦容积,分别给予疏肝和胃冲剂和吗丁啉治疗4周后复查胃排空功能,观察药物对患者胃排空功能的影响.结果 经药物治疗后,两组患者胃排空时间均较治疗前缩短,胃窦容积缩小.中药组胃半排空和胃全排空时间分别为(37.6±11.4)min和(78.9±14.6)min,西药组胃半排空和胃全排空时间分别为(39.2±14.0)min和(82.1±13.7)min;中药组治疗前15 min胃窦容积为(44.5±5.7)ml,治疗后15 min为(41.5±4.8)ml,治疗前105 min为(17.2±2.2)ml,治疗后105 min为(10.2±1.3)ml,西药组治疗前15 min胃窦容积为(45.1±5.8)ml,治疗后15 min为(39.4±4.5)ml,治疗前105 min为(15.3±2.3)ml,治疗后105 min为(9.3±1.0)ml,两组胃窦容积均呈逐渐减小趋势.结论 疏肝和胃冲剂对NUD患者胃排空功能有一定程度改善,为临床提供了一种疗效确切、无毒副作用的治疗NUD的新药.三维超声可有效检测NUD患者的胃排空功能,可临床应用推广.

Preliminary study on the gastric emptying function in patients with non-ulcer dyspepsia using three-dimensional ultrasonography

Objective To explore the diagnostic value of three-dimensional ultrasonography on gastric emptying function in patients with non-ulcer dyspepsia(NUD).Methods Sixty patients with NUD were divided randomly into chinese medicine group(n=30) and western medicine group(n=30).Gastric emptying time and antral volume were measured using three-dimensional ultrasonography.Gastric emptying function was reviewed 4 weeks after treatment.The efficacies of both drugs were assessed.Results After treatment,gastric emptying time and antral volume were lower than before treatment in the two groups.In chinese medicine group,half-time gastric emptying and all-time gastric emptying were(37.6±11.4)min and(78.9±14.6)min,respectively.In western medicine group,half-time gastric emptying and all-time gastric emptying were(39.2±14.0)min and(82.1±13.7)min,respectively.In chinese medicine group,gastric antral volume 15 min before treatment was(44.5±5.7)ml,15 min after treatment was(41.5±4.8)ml,105 min before treatment was(17.2±2.2)ml and 105 min after treatment was(10.2±1.3)ml.In western medicine group,gastric antral volume 15 min before treatment was(45.1±5.8)ml,15 min after treatment was(39.4±4.5)ml,105 min before treatment was(15.3±2.3)ml and 105 min after treatment was(9.3±1.0)ml.Gastric antral volume of the two groups showed a decreasing tendency.Conclusion Gastric emptying function in patients with NUD has a certain improvement through taking shuganhewei granule.It provides a new drug with curative effect and no side effects for treating NUD.Three-dimensional ultrasonography can be effectively detected gastric emptying function in patients with NUD,which may be of clinical application.