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胃转流术对代谢综合征改善作用的研究进展
引用本文:戴露倢,王瑜,王烈,黄盛. 胃转流术对代谢综合征改善作用的研究进展[J]. 中国普外基础与临床杂志, 2011, 18(2)
作者姓名:戴露倢  王瑜  王烈  黄盛
作者单位:1. 安徽医科大学第一临床医学院,安徽合肥,230032
2. 南京军区福州总医院普通外科,福建福州,350025
基金项目:福建省重点科技计划项目(项目编号:2009Y0039); 南京军区医药卫生科研重点专项(项目编号:09Z031)~~
摘    要:目的探讨胃转流术(GBP)对代谢综合征(MS)的影响及其作用机理。方法通过复习文献,回顾分析GBP对糖脂代谢和血压变化的影响。结果 GBP术后数天内,70%以上MS患者血糖、血脂达正常水平,血压控制有明显改善,而体重减轻迟于血糖、血脂变化。饮食、胃肠激素、脂肪细胞因子、脂肪分布等因素的改变参与GBP对MS的改善作用。结论 GBP似乎对控制MS有原发的、独立的影响,而非继发于对肥胖症的治疗。

关 键 词:代谢综合征  胃转流  胰岛素抵抗  糖尿病  

Review on Remission of Metabolic Syndrome after Gastric Bypass
DAI Lu-jie,WANG Yu,WANG Lie,HUANG Sheng. Review on Remission of Metabolic Syndrome after Gastric Bypass[J]. Chinese Journal of Bases and Clinics In General Surgery, 2011, 18(2)
Authors:DAI Lu-jie  WANG Yu  WANG Lie  HUANG Sheng
Affiliation:DAI Lu-jie1,WANG Yu2,WANG Lie2,HUANG Sheng2.1.The First Clinical Medicine,Anhui Medical University,Hefei 230032,Anhui Province,China,2.Department of General Surgery,Fuzhou General Hospital of Nanjing Military Area Command,Fuzhou 350025,Fujian Province
Abstract:Objective To explore the effect of gastric bypass(GBP) on metabolic syndrome(MS) and the related mechanisms.Methods The literatures addressed the effect of GBP on glucose metabolism and blood pressure were retrospectively analyzed.Results It showed that GBP achieved durable level of blood glucose,remission of dylipidemia and hypertension,however,which occurred before significant weight loss.The changes of many factors such as food intake,gastrointestinal hormones,adipocytokines,fat distribution might be inv...
Keywords:Metabolic syndrome  Gastric bypass  Insulin resistance  Diabetes mellitus  
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