Correlation between testicular tissue and H-Y phenotype in intersex patients |
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Authors: | U. Mü ller,,A. Mayerová ,,B. Debus,,M. Fraccaro,,S. Gilgenkrantz,,J. Glatzl,,K. Madan,,R. A. Pfeiffer,,A. Prader, O. Zuffardi |
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Affiliation: | Institute of Human Genetics, University of Freiburg, Freiburg, FRG;Centre Hospitalier de Mulhouse, Hôpital du Hasenrain, Mulhouse, France;Istituto di Biologia Generale e Genetica Medica, University of Pavia, Pavia, Italy;Centre Régional de Transfusion Sanguine et d'Hématologie de Nancy, Nancy, France;Universitätsklinik für Kinderheilkunde, Innsbruck, Austria;Institute of Human Genetics, Cytogenetics Laboratory, ZP009, AZVU, Free University, Amsterdam, The Netherlands;Institute of Human Genetics and Anthropology, University of Erlangen, Erlangen, FRG;Kinderspital Zürich, Zurich, Switzerland |
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Abstract: | H-Y antigen was tested in 13 humans with testicular tissue and disturbed primary and/or secondary sex differentiation. All cases typed H-Y positive. This finding is in agreement with the idea that testicular tissue only differentiates in the presence of H-Y antigen. |
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Keywords: | H-Y antigen intersex patients testis differentiation |
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