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GOUT AND HYPERURICAEMIA IN SYSTEMIC LUPUS ERYTHEMATOSUS
Authors:FROCHT, A.   LEEK, J. C.   ROBBINS, D. L.
Affiliation:Division of Rheumatology, Department of Internal Medicine, School of Medicine, University of California at Davis Davis, CA 95616, USA
Abstract:Coexistent gout and systemic lupus erythematosus (SLE) havereceived increasing attention. An additional case is reportedand published cases reviewed. Common clinical features of thisgroup include nephritis, diuretic and corticosteroid therapyand a tendency to be older and more frequently male. Prevalenceof hyperuricaemia (HU) was assessed in 38 patients with SLE.HU was found in 29% and was closely associated with renal involvementparticularly proteinuria and diuretic therapy. The presentationof gout in SLE may be modified or suppressed by anti-inflammatorytherapy and may be misinterpreted as SLE arthritis. KEY WORDS: Hyperuricaemia, Diuretics, Renal failure, Steroids
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