GOUT AND HYPERURICAEMIA IN SYSTEMIC LUPUS ERYTHEMATOSUS |
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Authors: | FROCHT, A. LEEK, J. C. ROBBINS, D. L. |
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Affiliation: | Division of Rheumatology, Department of Internal Medicine, School of Medicine, University of California at Davis Davis, CA 95616, USA |
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Abstract: | Coexistent gout and systemic lupus erythematosus (SLE) havereceived increasing attention. An additional case is reportedand published cases reviewed. Common clinical features of thisgroup include nephritis, diuretic and corticosteroid therapyand a tendency to be older and more frequently male. Prevalenceof hyperuricaemia (HU) was assessed in 38 patients with SLE.HU was found in 29% and was closely associated with renal involvementparticularly proteinuria and diuretic therapy. The presentationof gout in SLE may be modified or suppressed by anti-inflammatorytherapy and may be misinterpreted as SLE arthritis. KEY WORDS: Hyperuricaemia, Diuretics, Renal failure, Steroids |
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