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Transfusion-related acute lung injury
Authors:R. O. B. Gans  V. A. M. Duurkens  A. A. van Zundert  S. J. Hoorntje
Affiliation:(1) Department of Medicine, Catharina Hospital Eindhoven, The Netherlands;(2) Department of Medicine, Free University Hospital, De Boelelaan 1117, NL-1081 HV Amsterdam, The Netherlands
Abstract:
Noncardiogenic pulmonary edema after transfusion therapy is an infrequent but hazardous complication. The occurrence of this entity is linked to the presence of circulating leukoagglutinins. The clinical features are described on the basis of four cases. The hemodynamic changes, underlying mechanisms and therapeutic strategies are discussed.
Keywords:Transfusion  Noncardiogenic  Pulmonary edema  Leukoagglutinins
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