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Peroxisome proliferator‐activated receptor‐β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53‐ and SOX2‐mediated cell differentiation
Authors:Pei‐Li Yao  Liping Chen  Tomasz P. Dobrzański  Bokai Zhu  Boo‐Hyon Kang  Rolf Müller  Frank J. Gonzalez  Jeffrey M. Peters
Affiliation:1. Department of Veterinary and Biomedical Sciences and The Center of Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania;2. Non‐clinical Research Institute, Chemon, Jeil‐Ri, Yangji‐Myeon, Cheoin‐Gu, Yongin‐Si, Gyeonggi‐Do, Korea;3. Institute of Molecular Biology and Tumor Research, Center for Tumor Biology and Immunology, Philipps University, Marburg, Germany;4. Laboratory of Metabolism, National Cancer Institute, Bethesda, Maryland
Abstract:
Keywords:neuroblastoma  p53  peroxisome proliferator‐activated receptor‐β      retinoid acid  SOX2
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