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光学相干断层成像术检测近视眼视网膜神经纤维层厚度的特点
引用本文:曹东,贺翔鸽,刘莛,孙强. 光学相干断层成像术检测近视眼视网膜神经纤维层厚度的特点[J]. 国际眼科杂志, 2008, 8(10): 2044-2048
作者姓名:曹东  贺翔鸽  刘莛  孙强
作者单位:第三军医大学大坪医院野战外科研究所眼科,中国重庆市,400042
摘    要:目的:探讨光学相干断层成像术(optical coherence tomography,OCT)检测近视眼视盘周围视网膜神经纤维层(ret-inal nerve fiber layer,RNFL)厚度的特点及其与屈光度的关系。方法:对5~40岁正常对照眼61例68眼,近视眼152例205眼,应用Stratus OCTTM3000,RNFL3.4程序对视盘为中心直径3.4mm的RNFL进行检测。结果:近视眼RFNL厚度7∶00和11∶00位最大,3∶00位最小,上象限(S)、下象限(I)平均值接近并(颞侧象限平均值(T)(鼻侧象限平均值(N)。正常眼组与低度、中度和高度近视眼组对应RNFL厚度相关参数组间比较:7∶00和11∶00,Smax,Imax,Smax/Imax,Max-Min差异均无显著性,3∶00、4∶00和N差异均有显著性。控制年龄因素条件下,近视眼RNFL厚度部分参数(上方和鼻侧居多)与等效球镜度数有较弱的负线性相关直线趋势,而部分参数(下方和颞侧居多)与等效球镜度数无直线性相关趋势。结论:近视眼视盘鼻侧RNFL厚度已变薄,中度和高度近视眼更明显,而颞侧和颞下RNFL变化不明显。

关 键 词:视网膜神经纤维层  光学相干断层成像术  近视  青光眼

Study of the retinal nerve fiber layer thickness measurement using optical coherence tomography in myopic subjects
Dong Cao,Xiang-Ge He,Ting Liu,Qiang Sun. Study of the retinal nerve fiber layer thickness measurement using optical coherence tomography in myopic subjects[J]. International Eye Science, 2008, 8(10): 2044-2048
Authors:Dong Cao  Xiang-Ge He  Ting Liu  Qiang Sun
Affiliation:Department of Ophthalmology,Daping Hospital,the Third Military Medical University,Chongqing 400042,China
Abstract:AIM:To evaluate the characteristics of peripapillary retinal nerve fibre layer(RNFL)thickness parameters and to investigate the relationship between RNFL thickness and the diopter in myopic Chinese subjects. METHODS:The peripapillary RNFL of 205 myopic eyes and 68 normal control eyes with aged from 5 to 40 years were imaged on the Stratus OCTTM 3000.Thickness of the RNFL around the disc was determined with 3.4mm dia-meter circle OCT scan,and it was measured and analyzed using the RNFL thickness average anal...
Keywords:retinal nerve fiber layer  optical coherence tomography  myopia  glaucoma  
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