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| 人工培养云南冬虫夏草菌粉的抗炎效果的动物实验研究 | |
| 引用本文： | 王峰,王玲,张才军,李冰雪. 人工培养云南冬虫夏草菌粉的抗炎效果的动物实验研究[J]. 昆明医学院学报, 2009, 30(2): 36-39 |
| 作者姓名： | 王峰 王玲 张才军 李冰雪 |
| 作者单位： | 1. 云南医学高等专科学校免疫与病原生物学教研室,云南,昆明,650031 2. 昆明医学院免疫与病原微生物教研室,云南,昆明,650031 |
| 基金项目： | 云南省教育厅科研立项基金 |
| 摘 要： | 目的研究人工培养云南本土冬虫夏草菌粉（YNCS）在ICR小鼠体内的抗炎效果．方法ICR小鼠随机分组，每日用不同剂量的YNCS灌胃，观察YNCS对二甲苯致小鼠耳廓肿胀的影响和对小鼠腹腔毛细血管通透性的影响，以判断YNCS的抗炎效果．结果YNCS低、中、高剂量对二甲苯所致的小鼠耳廓肿胀有显著抑制作用（P〈0．05），但对小鼠腹腔毛细血管通透性影响不明显．结论YNCS具有一定抑制肿胀的抗炎效果． |
| 关 键 词： | 冬虫夏草 抗炎 ICR小鼠 云南 |
Anti-inflammation Effects of Yunnan Cordyceps Sinensison |
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| WANG Feng,WANG Ling,ZHANG Cai-Jun,LI Bing-Xue. Anti-inflammation Effects of Yunnan Cordyceps Sinensison[J]. Journal of Kunming Medical College, 2009, 30(2): 36-39 | |
| Authors: | WANG Feng WANG Ling ZHANG Cai-Jun LI Bing-Xue |
| Affiliation: | WANG Feng, WANG Ling, ZHANG Cai-Jun, LI Bing-Xue (1) Dept. of Microbiology and Immunology of Yunnan Medical College, Yunnan Kunming 650031; 2 ) Dept. of Microbiology and Immunology, Kunming Medical University, Kunming Yunnan 650031, China) |
| Abstract: | Objective To study the anti-inflammatory effects of cultured Yunnan Cordyceps sinensis （YNCS） in ICR mice. Methods Different dosages of YNCS were intragastriced to ICR mice every day which were randomly divided into several groups. The YNCS effect were observed in swelling of mouse pinnea caused by dimethylbenzene and capillary vessel penetrating experiment, in order to study YNCS anti-inflammatory effects. Results Various doses of YNCS inhibited the swelling of mouse pinnea degree of ICR mice （P 〈 0.05） , but YNCS had no significant effect on capillary vessel penetrating. Conclusion YNCS has anti-inflammation effects to some extent. |
| Keywords: | Cordyceps Sinensison Anti-inflammation ICR mouse Yunnan |
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