扩散峰度成像的基本原理及其在脑肿瘤中的应用

扩散峰度成像（DKI）是近年发展起来的一项新的MR扩散加权成像（DWI）技术，不同于传统的DWI及扩散张量成像（DTI），DKI主要是通过描述组织内水分子扩散运动偏离正态分布的程度，评价组织的微结构，间接反映组织生理、病理情况。DKI目前已广泛应用于中枢神经系统的临床研究，尤其在脑肿瘤方面。对DKI的基本原理及其在脑肿瘤中的临床应用予以综述。

Diffusional kurtosis imaging: Basic principles and applications in brain tumors

Diffusional kurtosis imaging(DKI) is a recent developed novel diffusion-weighted magnetic resonance imaging. Different from diffusion weighed imaging and diffusion tensor imaging(DTI), DKI can quantify the degree of water diffusion departure from a Gaussian form to delineate microstructure in tissue, so that it can reflect physiological and pathological conditions. Recently, DKI have been widely used in assessment of central nervous system, especially in brain tumors. In this article we aimed to summarize the principles of DKI and its application in brain tumors.