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The detection by cellular electrophoresis of surface antibodies in human lymphocytes
Authors:G. Bert   Donatella Lajolo Di Cossano     Paola Pecco
Abstract:The electrophoretic mobility of peripheral blood lymphocytes from human subjects with positive Mantoux tests was measured before and after treatment with purified protein derivative. Lymphocytes from subjects with negative Mantoux reactions were used as controls. A large number of the first group lymphocytes showed a reduction of electrophoretic mobility and hence of the surface electrical charge. The mobility of the control cells submitted to the same treatment was unchanged. The possible presence of cytophilic antibodies or of cellular specific receptors on the lymphocyte surface is discussed.
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