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Preparative electrophoretic separation of normal and neoplastic human bone marrow cells |
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| Authors: | J. C. F. Schubert F. Walther E. Holzberg G. Pascher K. Zeiller |
| Affiliation: | (1) Zentrum der Inneren Medizin, Abteilung für Hämatologie, der Universität Frankfurt a. M., Germany;(2) Max-Planck-Institut für Eiweiß- und Lederforschung, München |
| Abstract: | Summary Bone marrow cells of patients with chronic myeloid leukemia, monocytic leukemia, myeloblast leukemia, chronic lymphatic leukemia, typical and atypical plasma cell myeloma and M. Waldenström were separated by free flow electrophoresis and their distribution profiles compared with profiles of normal bone marrow cells. Except for myeloma cells, the pathologic cells possess the same electrophoretic mobility as their normal counterparts. Atypical or typical myeloma cells show a much faster mobility than normal plasma cells. The importance of these results is discussed. Abbreviations EPM electrophoretic mobility. |
| Keywords: | Electrophoretic cell separation electrophoretic mobility of human bone marrow cells Leukemia Myeloma |
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