Rezidivierende Meningitis bei familiärem Mangel der achten Komponente des Komplementsystems |
| |
| Authors: | H. Keller S. Löke G. M. Hänsch D. Jentschura H. Gerhard D. L. Heene |
| |
| Affiliation: | (1) I. Medizinische Klinik, Klinikum Mannheim der Universität Heidelberg, Germany;(2) Institut für Immunologie der Universität Heidelberg, Germany |
| |
| Abstract: | ![]()
Summary An 18-year-old man suffered from recurrent bacterial meningitis. Investigation of the complement system revealed deficiency of the 8th complement component (C8) in the patient and his sister. Genetic defects of the terminal complement components C5 to C8 predispose toNeisseria infections, probably due to a lack in bacteriolytic activity. It is to be noted that 1 year ago the patient had been hospitalized for a culture-proved pneumococcal meningitis. |
| |
| Keywords: | Complement system C8-deficiency Meningococcal meningitis |
| 本文献已被 SpringerLink 等数据库收录！ |
