奥曲肽联合泮托拉唑治疗肝硬化合并急性上消化道出血的临床效果分析

目的 研究奥曲肽联合泮托拉唑在肝硬化合并急性上消化道出血治疗中的作用.方法 92例急性上消化道出血患者,根据治疗措施的不同分为对照组及实验组,每组46例.对照组行泮托拉唑治疗,实验组行奥曲肽联合泮托拉唑治疗.对比两组患者的止血时间、住院时间、不良反应发生情况及症状体征改善时间.结果 实验组患者的止血时间(26.14±3...

Analysis of the clinical effect of octreotide combined with pantoprazole in the treatment of liver cirrhosis complicated with acute upper gastrointestinal hemorrhage

Objective To study the effect of octreotide combined with pantoprazole in the treatment of liver cirrhosis complicated with acute upper gastrointestinal hemorrhage.Methods A total of 92 patients with acute upper gastrointestinal hemorrhage were divided into control group and experimental group according to different treatment measures,with 46 cases in each group.The control group was treated with pantoprazole,and the experimental group was treated with octreotide and pantoprazole.The hemostasis time,hospitalization time,occurrence of adverse reactions,and improvement time of symptoms and signs of the two groups were compared.Results The hemostasis time(26.14±3.21) h and hospitalization time(5.14±1.36) d of the experimental group were shorter than(47.14±3.01) h and(6.10±1.02) d of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions 4.35% in the experimental group was lower than 17.39%in the control group,and the difference was statistically significant(P<0.05).The negative-conversion time of fecal occult blood(2.58±0.25) d,recovery time of bowel sounds(2.74±0.25) d,and disappearance time of hematemesis(24.74±6.20) h in the experimental group were shorter than(4.58±0.25) d,(4.25±1.25) d,and(28.41±7.25) h in the control group,and the difference was statistically significant(P<0.05).Conclusion Octreotide combined with pantoprazole has definite effect and high safety on patients with liver cirrhosis and acute upper gastrointestinal hemorrhage,which can effectively eliminate inflammation and promote the rapid recovery of patients,and it is worthy of application and application.