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蒙药消肿散涂膜剂皮肤刺激和皮肤过敏实验研究
引用本文:王锋,李文娜,但家立,夏嫱,张述禹. 蒙药消肿散涂膜剂皮肤刺激和皮肤过敏实验研究[J]. 遵义医学院学报, 2008, 31(3): 243-244
作者姓名:王锋  李文娜  但家立  夏嫱  张述禹
作者单位:1. 遵义医学院珠海校区,广东,珠海,519041
2. 内蒙古医学院药学院,内蒙古,呼和浩特,010059
摘    要:
目的对消肿散涂膜剂皮肤的刺激性和致敏性进行了动物实验观察。方法以家兔为模型进行一次给药皮肤刺激和多次给药皮肤刺激实验,以豚鼠为模型观察涂膜剂的皮肤致敏作用。结果消肿散涂膜剂对家兔皮肤未见任何刺激作用,也不引起豚鼠出现过敏反应。结论消肿散涂膜剂是一种安全性很高的外用新剂型。

关 键 词:消肿散涂膜剂  刺激性  过敏性

Study of the skin irritation and skin allergenic effect of XIAOZHONGSAN paint
WANG Feng,LI Wen-na,DAN Jia-li,XIA Qiang,ZHANG Shu-yu. Study of the skin irritation and skin allergenic effect of XIAOZHONGSAN paint[J]. Acta Academiae Medicine Zunyi, 2008, 31(3): 243-244
Authors:WANG Feng  LI Wen-na  DAN Jia-li  XIA Qiang  ZHANG Shu-yu
Affiliation:WANG Feng 1,LI Wen-na1,DAN Jia-li1,XIA Qiang1,ZHANG Shu-yu2(1. Zunyi Medical College,Zhuhai Campus,Zhuhai 519041,China,2. Inner Mongolia Medical College,pharmacy faculty,Neimenggu Huhehaote,010059,China)
Abstract:
Objective To study the skin irritation and skin allergenic effect of XIAOZHONGSAN paint. Methods Once and multiple dosing skin irritation test was carried out with rabbit model,and skin sensitization experiment was observed with guinea pig . Results XIAOZHONGSAN paint had no any irritant effect on rabbit skin and no allergic response induced in guinea pig. Conclutions XIAOZHONGSAN paint is a safety agent for external application.
Keywords:XIAOZHONGSAN paint  irritation  allergy  
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