| 大疱性系统性红斑狼疮1例 |
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| 引用本文： | 黄怀球,赖维,朱国兴,陆春,万苗坚,苏向阳,顾有守. 大疱性系统性红斑狼疮1例[J]. 岭南皮肤性病科杂志, 2004, 11(3): 275-276,278 |
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| 作者姓名： | 黄怀球 赖维 朱国兴 陆春 万苗坚 苏向阳 顾有守 |
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| 作者单位： | 1. 广州中山大学附属第三医院皮肤性病科,广东,广州,510630
2. 广东省皮肤性病防治研究所,广东,广州,51000 |
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| 摘 要： | 分析报告1例大疱性系统性红斑狼疮。患者以全身皮肤粘膜起红斑、水疱为表现起病，伴有口腔溃疡、双膝关节疼痛，尿蛋白3 ，ANA阳性1：160颗粒型，ds-DNA抗体阳性，ENA阳性、SS-A阳性。取躯干部皮损行组织病理活检，皿染色示：表皮下水疱，真皮浅层水肿，真皮乳头见中性粒细胞聚集，免疫病理示基底膜带可见IgG呈颗粒状沉积，符合大疱性系统性红斑狼疮病理改变。该病例为大疱性系统性红斑狼疮。
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| 关 键 词： | 大疱性系统性红斑狼疮 抗体阳性 水疱 真皮 皮下 ANA 双膝关节疼痛 染色 颗粒状 乳头 |
| 文章编号： | 1009-8968(2004)03-0275-03 |
| 修稿时间： | 2004-02-10 |
Systemic Lupus Erythematosus With the Manifestations of Bullous:A Case Report |
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| HUANG Huai-qiu,LAI Wei,ZHU Guo-xing,LU Chun,WAN Miao-jian,SU Xiang-yang,GU You-shou. Systemic Lupus Erythematosus With the Manifestations of Bullous:A Case Report[J]. Southern China Journal of Dermato-Venereology, 2004, 11(3): 275-276,278 |
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| Authors: | HUANG Huai-qiu LAI Wei ZHU Guo-xing LU Chun WAN Miao-jian SU Xiang-yang GU You-shou |
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| Abstract: | Objective:We report a case of systemic lupus erythematosus with erythema, chronic vesicobullous lesions, oral ulcer and both knee joint pain. ANA(antinuclear antibody) and ds-DNA is presented in a high titer in the patient, and both ENA and SS-A were positive. Biopsy specimen revealed subepidermal blister. Indirect immunofluorescence was adopted for IgG test was showed the positive reaction. The clinical manisfestations and laboratory findings were the diagnosis of systemic lupus erythematosus.[ |
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| Keywords: | systemic lupus erythematosus |
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