代谢综合征三种诊断标准在广东省人群中的应用对比

目的比较2005年美国国家胆固醇教育计划成人治疗组第三次报告修订版（NCEP—ATPⅢ）、2005年国际糖尿病联盟（IDF）及2004年中华医学会糖尿病学会分会（CDS）提出的代谢综合征（MS）诊断标准在广东省人群中应用的异同及适用性。方法2007年1～6月在广东省人民医院体检中心进行资料搜集，随机选取资料完备的1349例体检人员为研究对象，分别应用NCEP—ATPⅢ、IDF和CDS标准诊断MS，按三种诊断标准估计MS患病率并比较所得患病率水平的差异，分析各定义下诊断MS的一致性。结果NCEP—ATPⅢ、IDF和CDS三种标准诊断的MS患病率分别是24．3％、20．3％和11．4％，以NCEP—ATPⅢ标准诊断的MS患病率最高（P〈0．01）；NCEP—ATPⅢ与IDF、IDF与CDS、NCEP—ATPⅢ与CDS两两间的一致检出率分别是93．6％、85．8％和85．0％，NCEP—ATPⅢ与IDF标准的一致检出率最高。结论三种诊断标准在MS的诊断结果上存在差异，以NCEP—ATPⅢ标准诊断的患病率最高，比较适合广东人群。提示制定合理的MS诊断标准势在必行。

Comparison of three criteria for metabolic syndrome applied to Guangdong population

Objective To compare three applications with three different definitions for metabolic syndrome, which are proposed by modification of the National Cholesterol Education Program Adult Treatment Panel Ill （NCEP- ATPⅢ ） in 2005, International Diabetes Federation （IDF） in 2005 and Chinese Diabetes Society （CDS） in 2004. The study .sample was drawn from Guangdong population. Methods The data of 1349 participants was collected in the Physical Examination Center of Guangdong Provincial People ＇ s Hospital from January to June in 2007. MS was diagnosed with the three criteria mentioned above respectively. The prevalence of MS and its diagnostic components and the unity of the three criteria were analyzed. Results According to NCEP - ATP Ⅲ , IDF and CDS, the prevalence of metabolic syndrome were 24.3 %, 20.3 % and 11.4 % respectively. The prevalence of MS diagnosed with NCEP - ATP Ⅲ was significantly higher than those with the other two criteria Ⅲ （ P〈 0.01 ）. Among all participants, the consistency in diagnosis of MS was 93.6% by the NCEP-ATPⅢ and IDF, 85.8% by IDF and CDS, and 85.0% by NCEP-ATPⅢ and CDS. The consistency between NCEP - ATPⅢ and IDF criterion was the highest. Conclusion There were significant differences among three criteria to diagnose MS in Guangdong population, while the prevalence diagnosed with NCEP ATPⅢ in 2005 is the highest.It seemed that the NCEP ATPⅢ criterion was the most suitable criterion for Duangdong population. A universally accepted criterion for metabolic syndrome should be worked out.