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Prognostic importance of human papillomavirus type 16 DNA in cervical cancer.
Authors:F Girardi  P Fuchs  J Haas
Institution:Department of Obstetrics and Gynecology, University of Graz, Austria.
Abstract:Human papillomavirus (HPV) type 16 DNA is frequent in invasive cervical cancers. Among 43 patients with invasive cervical cancer, HPV-16-positive tumors spread to the parametrial and pelvic lymph nodes significantly more often than did HPV-16-negative tumors (P less than 0.05). Demonstration of HPV-16 DNA in invasive cervical cancers may be an additional prognostic factor for this disease.
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