| 消瘤散联合肝动脉化疗栓塞术治疗中晚期肝癌近期疗效观察 |
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| 引用本文： | 吴眉,高月求,张斌,李运东,张涛,吴昆仑. 消瘤散联合肝动脉化疗栓塞术治疗中晚期肝癌近期疗效观察[J]. 上海中医药杂志, 2018, 52(4): 56-58 |
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| 作者姓名： | 吴眉 高月求 张斌 李运东 张涛 吴昆仑 |
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| 作者单位： | 上海中医药大学附属曙光医院肝病科;上海中医药大学曙光临床医学院;第二军医大学附属公利医院中医科; |
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| 基金项目： | 上海中医药大学附属曙光医院“四明”青年基金项目(SGKJ-201718)；上海市卫计委基层名老中医专家传承研究工作室建设项目(jezygzs-003) |
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| 摘 要： | ![]()
目的观察消瘤散联合肝动脉化疗栓塞术治疗中晚期肝癌的近期疗效。方法将66例中晚期肝癌患者随机分为治疗组和对照组,每组33例。两组均予肝动脉化疗栓塞术,治疗组在肝动脉化疗栓塞术前7天开始服用中药消瘤散。术后1个月评价近期疗效,观察肝功能相关实验室指标(ALT、AST、TBIL、ALB)、甲胎蛋白(AFP)、凝血酶原时间(PT)、生存质量KPS评分变化,以及不良反应发生情况。结果 (1)治疗组有效率、疾病控制率分别为63.6%、81.8%,对照组分别为45.5%、75.8%,治疗组近期疗效优于对照组(P0.05)。(2)组内术后1个月与治疗前比较,治疗组ALT、AST、TBIL水平明显下降(P0.05),对照组ALT、AST水平升高(P0.05);组间术后1个月比较,ALT、AST、TBIL、ALB差异均有统计学意义(P0.05)。(3)组内术后1个月与治疗前相比,两组AFP水平下降(P0.05),KPS水平升高(P0.05);组间治疗后比较,AFP、PT、KPS差异有统计学意义(P0.05)。(4)治疗组、对照组总体不良反应发生率分别为78.8%、97.0%;组间比较,恶心呕吐、骨髓抑制及总体不良反应发生率差异有统计学意义(P0.05)。结论消瘤散联合肝动脉化疗栓塞术治疗中晚期肝癌,可提高近期疗效,提高患者生存质量,减少不良反应。
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| 关 键 词： | 中晚期肝癌 肝动脉化疗栓塞术 消瘤散 近期疗效 |
| 收稿时间： | 2017-12-18 |
Short-term efficacy of Xiaoliu Powder combined with transcatheter arterial chemoembolization in the treatment of advanced liver cancer |
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| WU Mei,GAO Yueqiu,ZHANG Bin,LI Yundong,ZHANG Tao and WU Kunlun. Short-term efficacy of Xiaoliu Powder combined with transcatheter arterial chemoembolization in the treatment of advanced liver cancer[J]. Shanghai Journal of Traditional Chinese Medicine, 2018, 52(4): 56-58 |
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| Authors: | WU Mei GAO Yueqiu ZHANG Bin LI Yundong ZHANG Tao WU Kunlun |
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| Affiliation: | Department of Hepatology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201210,China,Department of Hepatology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201210,China,Department of Hepatology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201210,China,Department of Hepatology,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201210,China,Shuguang Clinical Medical College,Shanghai University of Traditional Chinese Medicine,Shanghai 201210,China and Department of Chinese Medicine,Public Hospital Affiliated to Second Military Medical University,Shanghai 200135,China |
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| Abstract: | ![]()
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| Keywords: | advanced liver cancer transcatheter arterial chemoembolization Xiaoliu Powder short-term efficacy |
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