| 淫羊藿素及相关衍生物的抗肿瘤机制研究进展 |
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| 引用本文： | 胡吉梦,姜昊文. 淫羊藿素及相关衍生物的抗肿瘤机制研究进展[J]. 上海中医药杂志, 2018, 52(4): 107-112 |
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| 作者姓名： | 胡吉梦 姜昊文 |
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| 作者单位： | 复旦大学附属华山医院泌尿外科; |
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| 摘 要： | 综述淫羊藿素及相关衍生物的抗肿瘤机制研究进展。淫羊藿素及相关衍生物对不同类型肿瘤有抑制作用,其作用机制主要包括诱导细胞凋亡、调控细胞周期、抗血管生成、抑制肿瘤转移和免疫调节等。
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| 关 键 词： | 淫羊藿素 衍生物 肿瘤 分子机制 临床应用 综述 |
| 收稿时间： | 2017-08-20 |
Research progress on anti-tumor mechanisms of icaritin and its related derivatives |
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| HU Jimeng and JIANG Haowen. Research progress on anti-tumor mechanisms of icaritin and its related derivatives[J]. Shanghai Journal of Traditional Chinese Medicine, 2018, 52(4): 107-112 |
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| Authors: | HU Jimeng and JIANG Haowen |
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| Affiliation: | Department of Urology,Huashan Hospital Affiliated to Fudan University,Shanghai 200040,China and Department of Urology,Huashan Hospital Affiliated to Fudan University,Shanghai 200040,China |
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| Abstract: | This paper reviews the anti-tumor mechanisms of icaritin and its related derivatives. Icaritin and its related derivatives show the inhibitory effects on the tumors of different types. Its mechanisms mainly include induction of cell apoptosis,regulation of cell cycle,anti-angiogenesis,inhibition of tumor metastasis and immune regulation. |
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| Keywords: | icaritin derivative tumor molecular mechanism clinical application review |
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