LASEK、PRK和LASIK治疗高度近视的早期疗效比较

目的：评价比较采用LASEK、PRK和LASIK治疗高度近视的早期疗效。方法：回顾性分析比较LASEK、PRK和LASIK治疗高度近视各30眼的临床资料，其中LASEK治疗的为角膜较薄、不能行LASIK治疗的高度近视。LASEK、PRK和LASIK均采用NIDEKEC-5000型准分子激光治疗仪进行激光切削，术后随访6个月，对术后疼痛、haze、裸眼视力和屈光结果进行分析比较。结果：与PRK相比，LASEK术后疼痛轻，haze发生率低。比较LASEK术后6个月时裸眼视力与术前矫正视力．差异无显著性（P〉0．05）。比较术后1、2和6个月时LASEK、PRK或LASIK各组的屈光度值．差异无显著性（P〉0．05）。结论：LASEK在治疗高度近视时，可产生很好的早期疗效。LASEK较PRK术后反应轻，较LASIK手术安全性高，可避免LASIK中角膜瓣并发症的发生，更适合角膜较薄的高度近视治疗。

Early postoperative clinical comparison of laser subepithelial keratomileusis,photorefractive keratectomy and laser in situ keratomileusis

Objective;To assess the early clinical results of laser subepithelial keratomileusis for the correction of high myopia comparing with photorefractive ketatectomy and laser in situ keratomileusis.Methods;A retrospective comparative study of 90 eyes who had different treatment for the correction of myopia with NIDEK EC-5000 excimer laser.LASEK?PRK or LASIK was performed in 30 eyes respectively.LASEK-treated eyes had thinner cornea than average level.The postoperative pain,haze,uncorrected visual acuity (UCVA) and refractive outcome were evaluated and compared.All eyes completed a 6-month follow-up.Results;LASEK-treated eyes had lower postoperative pain and corneal haze than PRK-treated eyes.There were no significant differences between preoperative best spectacle-corrected visual acuity and UCVA at 6 months after surgery in LASEK group(P>0.05).There were no significant differences between LASEK and PRK(or LASIK)in refractive outcome at 1 month,2 months or 6 months after surgery(P>0.05).Conclusion;Laser subepithelial keratomileusis safely and effectively treated eye with high myopia on relatively thin cornea.It reduced the incidence of significant postoperative pain and corneal haze and may prevent the flap-related problems of laser in situ keratomileusis.LASEK appeared to be a safe and effective treatment for the correction of high myopia with thin cornea.