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A Chromosome Study on 97 Cases of Acute Nonlymphocytic Leukemia M2
引用本文:程范军,杨爱德,费洪宝. A Chromosome Study on 97 Cases of Acute Nonlymphocytic Leukemia M2[J]. 华中科技大学学报(医学英德文版), 1994, 14(1): 35-37. DOI: 10.1007/BF02888055
作者姓名:程范军  杨爱德  费洪宝
作者单位:Research Institute of Hematology,Xiehe Hospital,Tongji Medical University.Wuhan
摘    要:
(程范军)(杨爱德)(费洪宝)AChromosomeStudyon97CasesofAcuteNonlymphocyticLeukemiaM2¥HENFan-jun,YANGAi-de,FEIHong-bao(ResearchInstituteofHema...

收稿时间:1992-12-01

A chromosome study on 97 cases of acute nonlymphocytic leukemia M2
Chen Fan-jun,Yang Ai-de,Fei Hong-bao. A chromosome study on 97 cases of acute nonlymphocytic leukemia M2[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 1994, 14(1): 35-37. DOI: 10.1007/BF02888055
Authors:Chen Fan-jun  Yang Ai-de  Fei Hong-bao
Affiliation:(1) Research Institute of Hematology, Xiehe Hospital, Tongji Medical University, Wuhan
Abstract:
Chromosomal studies were performed in the same laboratory on 97 untreated cases of de novo acute nonlymphocytic leukemia M2.The overall incidence of chromosomal abnormality was 70.1% (68 out of 97 cases),which was higher in children(84. 2% )than in edults (61%).The male to female chromosomal abnormality ratio was nearly the same(male 71% and female 68. 4% .P>0.05).Hypodiploidy was the most common numerical abnormality(39%)and t (8;21) was the most common structural abnormality (48.1%) It the patients with t (8;21),64 5%(2) out of 31cases) male lost chromosome Y (-Y) and 33%(5 out of 15 cases)female lost one chromosomeX(-X).
Keywords:acute nonlymphocytic leukemia M2  chromosome
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