慢性阻塞性肺疾病的肺高分辨率CT呼气相研究

目的　分析慢性阻塞性肺疾病 (COPD)患者吸气相和呼气相高分辨率CT(HRCT)表现 ,对呼气相HRCT上的空气潴留征进行定量分析。方法　 44例COPD患者进行吸气相、呼气相HRCT和肺功能试验检查 ,分析其HRCT表现 ,统计双肺吸 -呼气相密度差值 (VD)和面积缩小率 (AD)、空气潴留评分值并与肺功能试验指标进行相关性分析。结果　 40例患者呼气相HRCT上出现空气潴留征 ,超出了吸气相异常征象的范围 ;双肺VD和AD、空气潴留评分值与肺功能试验指标显著相关 (Ρ <0 .0 5 )。结论　呼气相HRCT可以作为吸气相HRCT的补充手段 ,空气潴留征能够定量分析并且反映患者的肺功能状况

Quantitative Study of Expiratory Lung HRCT in the Patients with Chronic Obstruction Pulmonary Disease(COPD)

Objective To assess the findings on inspiratory and expiratory lung HRCT in COPD and to quantify the extension of air trapping on expiratory HRCT.Methods Inspiratory and expiratory HRCT scans were performed and studied in 44 patients with COPD. The inspiratory-expiratory value difference (VD), area decrease ratio (AD), air-trapping grading of bilateral lungs were calculated and correlated statistically with pulmonary function test (PFT) indexes.Results Air-trapping presented on expiratory HRCT in 40 patients which was out of the extent of the abnormal findings on inspiratory HRCT. There was significant correlation between VD, AD, air-trapping grading and PFT indexes. Conclusion Expiratory HRCT can be a supplement to inspiratory HRCT. The extension of air-trapping can be quantified and used in assessing pulmonary function of the patient.