| 卡那霉素在体外对A.healyi的杀伤作用 |
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| 引用本文： | 李红花,郑善子,孙昌元,李芳芳,金权鑫.卡那霉素在体外对A.healyi的杀伤作用[J].延边医学院学报,2010,33(2):102-104. |
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| 作者姓名： | 李红花 郑善子 孙昌元 李芳芳 金权鑫 |
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| 作者单位： | 延边大学基础医学院,免疫学与病原生物学教研部,吉林,延吉,133000 |
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| 摘 要： | 目的]观察卡那霉素在体外对棘阿米巴A.healyi的杀伤作用.方法]用1.0,10.0,100.0g/L卡那霉素和0.2,2.0g/L甲硝唑在体外培养棘阿米巴3,8,24,48h,观察用药前及不同培养时间的生长情况.结果]1.0g/L卡那霉素对棘阿米巴无抑制作用,10.0g/L卡那霉素在培养48h时及100.0g/L卡那霉素培养24h时抑制棘阿米巴生长,100.0g/L卡那霉素在培养48h时杀伤棘阿米巴.2.0g/L甲硝唑作用48h时仍无明显的杀伤作用.结论]在体外卡那霉素质量浓度为10.0g/L时对棘阿米巴有抑制作用,100.0g/L时具有杀伤作用.
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| 关 键 词： | 棘阿米巴属 卡那霉素 甲硝唑 |
Killing effects of the kanamycin to A. healyi in vitro |
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| LI Hong-hua,ZHENG Shan-zi,SUN Chang-yuan,LI Fang-fang,JIN Quan-xin.Killing effects of the kanamycin to A. healyi in vitro[J].Journal of Medical Science Yanbian University,2010,33(2):102-104. |
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| Authors: | LI Hong-hua ZHENG Shan-zi SUN Chang-yuan LI Fang-fang JIN Quan-xin |
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| Institution: | (Department of Immunology and Pathogenic Biology,Yanbian University College of Basic Medicine,Yanji 133000,Jilin,China) |
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| Abstract: | OBJECTIVE To observe the killing effects of kanamycin to acanthamoeba A.healyi in vitro.METHODS A.healyi was cultured with 1.0,10.0,100.0 g/L of the kanamycin and 0.2,2.0 g/L of the metronidazole in vitro to observe the growth status before medication and in different culture time.RESULTS 1.0 g/L of the kanamycin had no inhibitory effect to A.healyi,cultured for 48 h with 10.0 g/L of the kanamycin and 24 h with 100.0 g/L of the kanamycin inhibited the growth of A.healyi,but cultured for 48 h with 100.0 g/L of the kanamycin killed A.healyi.2.0 g/L of the metronidazole could not inhibit the growth of A.healyi.CONCLUSION 10.0 g/L and 100.0 g/L of the kanamycin have inhibitory or killing effects to the A.healyi in vitro,respectively. |
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| Keywords: | acanthamoeba kanamycin metronidazole |
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