Recurrent, multiple, calcified soft tissue metastases from osteogenic sarcoma without pulmonary involvement

Osteosarcoma (osteogenic sarcoma) metastasizes primarily to the lung. With the introduction of neoadjuvant chemotherapy as part of the treatment, the overall and disease-free survival rates have dramatically improved. In this case report, a young man with multiple soft tissue and bone metastases, including a rare large bone-forming retroperitoneal metastasis, is described. Despite the extensive extrapulmonary metastases, the patient did not develop pulmonary metastases in the 4 years following initial presentation of the primary tumour. Received: 16 December 1998 Revision requested: 14 January 1999 Revision received: 30 July 1999 Accepted: 1 August 1999