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| 术后认知功能障碍与中枢炎症 | |
| 引用本文： | 赵龙德,钱燕宁. 术后认知功能障碍与中枢炎症[J]. 麻醉与监护论坛, 2011, 0(6): 434-436 |
| 作者姓名： | 赵龙德 钱燕宁 |
| 作者单位： | [1]南京医科大学附属南京儿童医院麻醉科,210008 [2]南京医科大学第一附属医院麻醉科,210029 |
| 摘 要： | 术后认知功能障碍（postoperative cognmve dysfunction，POCD）好发予老年患者，虽已渐为熟知。但POCD的发病机制仍不清楚。中枢炎症反应可能是其发病机制之一．涉及神经退行性变．手术应激、细胞因子释放、GSK-3β和胶质细胞的活性等多因素。 |
| 关 键 词： | 术后认知功能障碍 中枢 炎症反应 |
Postoperative Cognitive Dysfunction and Inflammation of CNS |
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| Affiliation: | Rong-de Zhao, Yan-ling Qian Department of anesthesiology ,nanjing children＇s hospital affiliated to nanjing medical university,210008 ]Department of anesthesiology,the first hospital affiliated to nan]ing medical university,210029 |
| Abstract: | It has been know that POCD （postoperative cognitive dysfunction） often occur in elderly patients, but the pathogenic mechanisms remain unknown. Inflammation response of central nervous system（CNS） may be one of the mechanisms, which relate with many factors, such as neurodegenerative disease, surgical stress, cytokine release, GSK-3βand glial cells activation. |
| Keywords: | POCD CNS Inflammation response |
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