米非司酮治疗围绝经期功能失调性子宫出血30例分析

目的：探讨米非司酮治疗围绝经期功能失调性子宫出血（功血）的效果。方法：30例在门诊确诊为围绝经期功血的患者,每晚空腹口服米非司酮12.5mg连服3个月,于治疗前及治疗后1个月、2个月、3个月、B超监测子宫内膜厚度,同时分别查肝肾功能及血常规,结果：30例患者在服药期间均闭经,无子宫内膜增厚,肝肾功能均正常,血红蛋白均有不同程度的提高,贫血得到改善。讨论：米非司酮治疗围绝经期功能失调性子宫出血疗效肯定,无肝肾功能的损害,是一种安全有效的治疗方法,值得推广应用。

Analysis on Mifepristone in the Treatment of 30 Cases of Peri - menopausal Dysfunctional Uterine Bleeding

Objective： To discuss the effect of mifepristone in the treatment of peri-menopausal dysfunctional uterine bleeding. Method： 30 cases who were diagnosed as peri-menopausal dysfunctional uterine bleeding were orally taken 12.5mg of mifepristone every night for consecutive 3 months. The thickness of endometrium were detected under B-ultrasonic 1m, 2m and 3m before and after treatment. Hepatorenal function and blood routine were measured at the same time. Result： All the cases were in amenorrhea during period in a medicine. No increment thickness appeared, the liver kidney function was normal, hemoglobin all contain the exaltation of different degree, and anemic got the improvement. Conclusion： Mifepristone has certain effect in the treatment of peri-menopausal dysfunctional uterine bleeding. It is safe, effective and has no harm to liver kidney function, which is worth of spreading.