| Abstract: | ![]()
This paper considers the influence of human variations in the kinetics and dynamics of chemicals in food upon the formulation of food safety legislation. Legislation is designed to protect and benefit all and not solely specific groups or individuals within the population. A consideration of the adequacy of the safety factors used to calculate Acceptable Daily Intake (ADI) leads on to the discussion of those circumstances in which a part of the population may exceed the ADI for a particular chemical. The conclusion is that the ADI does take human variability into consideration and that current legislation is satisfactory and made more so through the surveillance of dietary additive and contaminant intakes in man. |
