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Reoperation for primary hyperparathyroidism
Authors:Per-Ola Granberg  Gunnar Johansson  Nils Lindvall  Ulf Öhman  Alexander Wajngot  Sigbritt Werner  Jan-Silvester Willems
Affiliation:Stockholm, Sweden
Abstract:
The reasons for failure of the initial exploration and the results of reoperation were analyzed in 53 patients with a diagnosis of primary hyperparathyroidism, 29 of whom were referred after initial operations elsewhere. Seventy-nine reoperations were performed. Sternotomy was used in 15 patients, and in retrospect was necessary in only 5. There was no operative mortality. The reasons for initial failure were incorrect diagnosis in 6 patients, true recurrence in 4 and persistent disease in 43. Persistence was caused by surgical failure in two thirds and pathology failure in one third. Of 47 patients reoperated on for hyperparathyroidism, 39 (83 percent) were cured, a rate warranting this type of surgery. Analysis of a long-term series of initial operations demonstrates a persistence rate of 5 percent (24 of 461) and a recurrence rate of 1 percent (4 of 461) in this disease. The need for reoperation was less than 1 percent over the recent 5 year period.
Keywords:Requests for reprints should be addressed to Ulf Öhman   MD   Department of Surgery   Karolinska Hospital   S-104 01 Stockholm   Sweden.
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