Isolation of a low molecular weight glycoprotein inhibitor of calcium phosphate precipitation from the extra-parotid saliva of macaque monkeys. |
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| Authors: | T E VanDyke M J Levine M C Herzberg S A Ellison D I Hay |
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| Affiliation: | 1. Department of Oral Biology. School of Dentistry, State University of New York at Buffalo, USA;2. Forsyth Dental Center, 140 The Fenway, Boston 15, MA 02115, U.S.A. |
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| Abstract: | A low molecular weight (9600) glycoprotein was isolated from monkey (Macaca arctoides) extra-parotid saliva by gel filtration on Sephadex G-200 and Sephadex G-50. Criteria of purity included immunodiffusion, immunoelectrophoresis and polyacrylamide gel electrophoresis. The molecule contained 76 per cent protein, 23.4 per cent carbohydrate and 0.6 per cent phosphorus. The glycoprotein was a potent inhibitor of calcium phosphate precipitation. |
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| Keywords: | To whom reprint requests should be addressed. |
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