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| 固本喘嗽康颗粒平喘、抗炎及免疫作用实验研究 | |
| 引用本文： | 甘雨,张宏,乔世举,朱希卓,乔敏,孟莉,包玉龙,杨文奇,付琳媛. 固本喘嗽康颗粒平喘、抗炎及免疫作用实验研究[J]. 中华中医药杂志, 2010, 0(2) |
| 作者姓名： | 甘雨 张宏 乔世举 朱希卓 乔敏 孟莉 包玉龙 杨文奇 付琳媛 |
| 作者单位： | 辽宁省中医药研究院;辽宁中医药大学; |
| 基金项目： | 辽宁省科技厅资助项目(No.2005225003-9)~~ |
| 摘 要： | 目的:观察固本喘嗽康颗粒的平喘、抗炎及免疫作用。方法:用卵蛋白雾化吸入致敏法建立大鼠哮喘模型,观察固本喘嗽康颗粒对大鼠引喘潜伏期和BALF中白细胞数的影响;用二甲苯及琼脂建立炎症模型观察固本喘嗽康颗粒对急性炎症及慢性炎症的作用;从体液免疫和细胞免疫两方面观察固本喘嗽康颗粒的免疫作用。结果:固本喘嗽康颗粒可明显延长大鼠引喘潜伏期,降低BALF中白细胞数;可明显对抗急性炎症和慢性炎症;对体液免疫和细胞免疫具有调节作用。结论:固本喘嗽康颗粒具有平喘、抗炎和免疫调节的作用。 |
| 关 键 词： | 固本喘嗽康颗粒 平喘 抗炎 免疫 |
Experimental study on antiasthmafic, anti-inflammatory and immunological effects of Gubenchuansoukang Granule |
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| GAN Yu,ZHANG Hong,QIAO Shi-ju,ZHU Xi-zhuo,QIAO Min,MENG Li,BAO Yu-long,YANG Wen-qi,FU Lin-yuan. Experimental study on antiasthmafic, anti-inflammatory and immunological effects of Gubenchuansoukang Granule[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 2010, 0(2) | |
| Authors: | GAN Yu ZHANG Hong QIAO Shi-ju ZHU Xi-zhuo QIAO Min MENG Li BAO Yu-long YANG Wen-qi FU Lin-yuan |
| Affiliation: | 1Liaoning Institute of TCM;Shenyang 110034;China;2Liaoning University of TCM;Shenyang 110032;China |
| Abstract: | Objective: To observe the antiasthmaf ic, anti-inflammatory and immunological effects of Gubenchuansoukang Granule. Methods: The rats asthma model was established by ovalbumin sensitization. The model was identified by the study of the asthma incubation period and the total white cells counts in bronchoalveolar lavage fluid (BALF). The anti-inflammatory effect was observed by the acute inflammation and chronic inflammation induced xylene and agar. To observe the effect of Gubenchuansoukang Granule on humora... |
| Keywords: | Gubenchuansoukang Granule Anti-asthma Anti-inflammation Immune |
| 本文献已被 CNKI 等数据库收录！ | |