CT/MRI影像融合对肺癌脑转移放射治疗靶区勾画的影响

背景与目的脑转移瘤靶区勾画的准确性一直是放射治疗的关键,CT/MRI融合技术提供了可行的方法 ,本研究旨在探讨CT/MRI图像融合技术在肺癌脑转移靶区勾画中的作用。方法将31例肺癌脑转移患者的增强CT和MRI图像传送至图像处理工作站,分别在CT和CT/MRI融合图像上勾画GTV,比较勾画后的GTV体积,分析最大平均误差及瘤周水肿对靶区勾画的影响。结果 CT/MRI融合图像上勾画的GTV明显小于CT图像上勾画的GTV;瘤周水肿对靶区勾画存在明显影响。结论 CT/MRI图像融合技术可以提高肺癌脑转移靶区勾画的准确性。

Impact of CT/MRI Image Registration on Target Delineation of Radiotherapy for Lung Cancer with Brain Metastasis

Background and objective Accurate target delineation in radiation therapy is a key component of the treatment regimen for brain metastasis for which CT/MRI fusion technology provides a feasible method.The aim of this study is to explore the role of CT/MRI image registration in target delineation for lung cancer with brain metastasis.Methods The image data of 31 patients were processed using Oncentra MasterPlan.The GTVs were delineated on CT and CT/MRI images,and their differences were compared to analyze the impact of the maximum average error and tumor edema on target delineation.Results The GTVs delineated on CT/MRI images were markedly smaller than those delineated on CT images.Target delineation was clearly influenced by edema.Conclusion The technology of CT/MRI image registration can improve the accuracy of target delineation for lung cancer with brain metastasis.