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| 两株小鼠肝癌细胞增殖状态比较研究 | |
| 引用本文： | 张晨,董瑞琪,侯力,白洁,凌茂英.两株小鼠肝癌细胞增殖状态比较研究[J].大连医科大学学报,2000,22(3):180-181. |
| 作者姓名： | 张晨 董瑞琪 侯力 白洁 凌茂英 |
| 作者单位： | 1. 解放军第210医院中医血液病研究所,辽宁,大连,116021 2. 大连陆军学院,辽宁,大连,116100 3. 大连医科大学病理学教研室,辽宁,大连,116027 |
| 摘 要： | 目的：探讨细胞增殖状态与细胞转移力的关系。方法：采用流式细胞术，测定两株腹水型肝癌细胞的ＤＮＡ含量，进而提供细胞增殖状态的信息。结果：Ｆ和Ｐ细胞的ＤＮＡ指数及细胞增殖指数均无显著性差异。Ｆ细胞的淋巴结转移瘤的Ｇ２／Ｍ期比率高于其原发瘤。结论：两株细胞的转移率与细胞的增殖状态无明显的相关性。 |
| 关 键 词： | 肝癌 细胞增殖状态 流式细胞术 细胞周期 |
| 文章编号： | 1000-5676 (2000) 03-0180-02 |
| 修稿时间： | 2000-04-17 |
The comparison between two hepatic tumor cell lines with different metastatic capacity on cell distribution |
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| ZHANG Chen,DONG Rui-qi,HOU Li.The comparison between two hepatic tumor cell lines with different metastatic capacity on cell distribution[J].Journal of Dalian Medical University,2000,22(3):180-181. | |
| Authors: | ZHANG Chen DONG Rui-qi HOU Li |
| Institution: | ZHANG Chen ,DONG Rui-qi ,HOU Li (Hematology Institute of Traditional Chinese Medicine,The 210th Hospital,Dalian 116021 China) |
| Abstract: | Objective:To investigate the relationship of cell cycle distribution and metastasis in two tumor cell lines.Methods:The DNA contents of two hepatic carcinoma cell lines were studied by flow cytometry.Results:The DNA index and proliferative index between higher metastatic F cell and lower metastatic P cell were no significant differences,but G 2/M phase of tumor cells with lymphatic metastasis were remarkably higher than that of F cell in non-metastasis.Conclusion:The two hepatic carcinoma cell lines with different lymph node metastatic capacities were no differences in cell proliferation. |
| Keywords: | flow cytometry cell Lines cell cycle distribution |
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