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Safety and Efficacy of Cabozantinib in Metastatic Renal-Cell Carcinoma: Real-World Data From an Italian Managed Access Program
Authors:Giuseppe Procopio  Michele Prisciandaro  Roberto Iacovelli  Enrico Cortesi  Giuseppe Fornarini  Gaetano Facchini  Giacomo Cartenì  Roberto Sabbatini  Gabriella Del Bene  Luca Galli  Claudia Caserta  Andrea Giovanni Multari  Marco Bregni  Francesco Massari  Sebastiano Buti  Ugo De Giorgi  Fable Zustovich  Michele Milella  Elena Verzoni
Affiliation:1. Department of Medical Oncology, Genitourinary Cancer Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy;2. Medical Oncology Unit, Azienda Ospedaliera Universitaria Integrata (AOUI), University of Verona, Verona, Italy;3. Department of Medical Oncology B, Policlinico Umberto I “Sapienza” University of Rome, Rome, Italy;4. Medical Oncology Department, IRCCS Azienda Ospedaliera Universitaria San Martino–IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy;5. Division of Medical Oncology, Department of Uro-Gynaecological Oncology, Istituto Nazionale Tumori Fondazione G. Pascale (IRCCS), Naples, Italy;6. Oncology Unit, Antonio Cardarelli Hospital, Naples, Italy;7. Department of Oncology and Hematology and Respiratory Disease, University Hospital, Modena, Italy;8. Department of Medical Oncology, San Camillo Forlanini Hospital, Rome, Italy;9. Department of Medical Oncology 2, Istituto Toscano Tumori, Pisa, Italy;10. Oncology Department, Santa Maria Hospital, Terni, Italy;11. Medical Oncology Unit, University of Siena, Siena, Italy;12. Ospedale di Circolo di Busto Arsizio, Busto Arsizio, Italy;13. Division of Oncology, S Orsola-Malpighi Hospital, Bologna, Italy;14. Medical Oncology Unit, University Hospital of Parma, Italy;15. Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy;16. San Martino Hospital, Medical Oncology, Belluno, Italy;17. Medical Oncology Unit, Istituto Nazionale Tumori Regina Elena (IFO), Rome, Italy;18. Medical Oncology Unit, Campus Bio-Medico University of Rome, Rome, Italy;19. Medical Oncology Unit, Camposampiero, Italy;20. Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy;21. Oncology Unit, Department of Oncology and Advanced Technologies, Arcispedale Santa Maria Nuova–IRCCS, Reggio Emilia, Italy;22. Division of Medical Oncology, San Luigi Gonzaga Hospital, Department of Oncology, University of Turin, Orbassano, Turin, Italy;23. Department of Medical Oncology, AOU Ospedali Riuniti, Università Politecnica delle Marche, Presidio San Salvatore, Pesaro, Italy;24. Division of Oncology, Institute for Cancer Research and Treatment, ASL CN2 Alba-Bra, Alba, Italy;25. Oncology Department, S. Giovanni Calibita’ Fatebenefratelli Isola Tiberina Hospital, Rome, Italy
Abstract:
Keywords:c-Met  Metastatic renal cell carcinoma  METEOR study  Targeted therapy  VEGF inhibitor
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