Granulocytic sarcoma: An atypical presentation in the oral cavity |
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Authors: | Eric T. Stoopler DMD res Pinto DMD Faizan Alawi DDS Sree Raghavendra DMD Ricardo Boyce Jr. DDS David Porter MD Thomas P. Sollecito DMD |
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Affiliation: | Assistant Professor of Oral Medicine, University of Pennsylvania School of Dental Medicine;Assistant Professor of Pathology, University of Pennsylvania School of Dental Medicine;Fellow, Department of Oral Medicine, University of Pennsylvania School of Dental Medicine;Associate Professor of Medicine, University of Pennsylvania School of Medicine;Associate Professor of Oral Medicine, University of Pennsylvania School of Dental Medicine. |
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Abstract: | Acute myelogenous leukemia (AMU is a hematologic disorder that is characterized by an abnormal proliferation of immature myeloid cells. Granulocytic sarcomas are clusters of leukemic myeloid cells that may develop as a result of AML. Oral manifestations of AML are common and often involve enlargements of the gingiva and/or mucosal tissue from direct leukemia cell infiltration. We describe the case history of a 50-year-old man who had an ulcera-tive lesion of the oral mucosa that was determined to be a granulocytic sarcoma of AML-M0 subtype. The combination of both the subtype and clinical presentation of the leukemia makes this presentation unusual, and to the best of our knowledge, of a type that has not been previously reported in the literature. |
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Keywords: | acute myelogenous leukemia granulocytic sarcoma |
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