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| 增殖细胞核抗原在食管鳞癌的表达 | |
| 引用本文： | 滕晓东 张晓娟. 增殖细胞核抗原在食管鳞癌的表达[J]. 肿瘤研究与临床, 1998, 10(3): 158-159 |
| 作者姓名： | 滕晓东 张晓娟 |
| 作者单位： | 南通医学院第二附属医院 |
| 摘 要： | 为检测增殖细胞核抗原（ＰＣＮＡ）在食管鳞癌的表达及其临床病理关系，对４９例手术切除的食管鳞癌标本，行免疫组化法检测单克隆抗体ｐｃ１０的表达。结果显示ＰＣＮＡ的表达强度与食管鳞癌的分化程度成反比，与有无淋巴结转移成正比，差异有显著性意义（Ｐ＜０．０５）；与肿瘤浸润深度无明显相关。提示ＰＣＮＡ的表达强度可反映食管鳞癌细胞增殖活力和转移能力 |
| 关 键 词： | 食管鳞癌 增殖细胞核抗原 免疫组织化学 |
EXPRESSION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS |
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| Teng Xiaodong,Zhang Xiaojuan,Liu Hongbing The Second Hospital of Nan Tong Medical Collage. EXPRESSION OF PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA) IN SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS[J]. Cancer Research and Clinic, 1998, 10(3): 158-159 | |
| Authors: | Teng Xiaodong Zhang Xiaojuan Liu Hongbing The Second Hospital of Nan Tong Medical Collage |
| Abstract: | In order to study the expression of proliferating cell nuclear antigen (PCNA) in esphageal squamous cell carcinoma (ESCC) and its clinicopathological significance,the expression of PCNA was analyzed by using a monoclonal antibody PC10 with immunohistochemical staining in 49 cases of ESCC. The staining intensity of PCNA was correlated with the tumor histologic grade and lymph node metastasis ( P <0 005) The expressive intensity of PCNA in ESCCs may suggest the cancer cell proliferative activity and metastatic ability. |
| Keywords: | Esphageal squamous cell carcinoma Proliferating cell nuclear antigen (PCNA) Carcinoma of the esphagus Immunohistochemistry |
| 本文献已被 CNKI 维普 等数据库收录！ | |