Diabetic osteopenia and circulating levels of vitamin D metabolites in type 2 (noninsulin-dependent) diabetes |
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| Authors: | H Ishida Y Seino S Matsukura M Ikeda M Yawata G Yamashita S Ishizuka H Imura |
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| Affiliation: | 1. Second Division, Department of Internal Medicine, Kyoto University School of Medicine, Kyoto, Japan.;2. Division of Metabolism and Clinical Nutrition, Kyoto University School of Medicine, Kyoto, Japan.;3. the Diabetes Center, Ikeda Clinic, Amagasaki, Japan.;4. Kitano Hospital, Osaka, Japan.;5. the Department of Biochemistry, Teijin Institute for Biomedical Research, Tokyo, Japan. |
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| Abstract: | ![]()
The degree of diabetic osteopenia and serum vitamin D metabolite levels were measured in 168 type 2 (noninsulin-dependent) diabetic patients. Based on six indices obtained by microdensitometry, we found the bone mass in 26.2% of diabetic patients to be clearly decreased and in 11.9% to be severely decreased. Our direct method of analysis of bone mass shows that diabetic osteopenia differs from typical osteoporosis in character. In addition, serum 24,25-dihydroxyvitamin D was significantly decreased (P less than 0.01), but 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D were similar to those of controls. |
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| Keywords: | Address reprint requests to Hitoshi Ishida MD Second Division Department of Internal Medicine Kyoto University School of Medicine Shogoin Kawahara-cho Sakyo-ku Kyoto 606 Japan. |
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