颅内神经元及混合性神经元-胶质瘤的MRI表现及病理对照

目的：探讨颅内神经元及混合性神经元-胶质瘤的病理及MRI表现，提高对其的认识。方法：回顾分析26例经手术病理证实的颅内神经元及混合性神经元-胶质肿瘤病例的临床、组织病理学及MRI影像学特点。结果：胚胎发育不良神经上皮瘤11例，幕上常见，以累及皮质为主，部分囊变，T1WI低信号，T2WI高信号，边缘清楚，水肿少见，增强不强化或轻度环壁结节强化；神经节细胞胶质瘤11例，多发幕上，T1WI以低信号为主，T2WI以高信号为主，其中2例信号混杂，病灶边缘多清楚，少见水肿或轻度水肿，增强不强化或轻度不均强化；中枢神经细胞瘤3例，均位于侧脑室，T1WI和T2WI呈混杂信号，内有囊变，增强明显不均强化；婴儿促纤维增生型节细胞胶质瘤1例，位于左额颞顶叶，呈大囊状，有纤维分隔，T1WI低信号为主，T2WI高信号为主。结论：颅内神经元及混合性神经元-胶质瘤的影像学表现不具有特异性，临床工作中，遇到类似影像学表现的病变，需紧密结合其临床表现。

MRI features and pathology of intracranial neuronal and mixed neuronal-glial tumor

Objective： To investigate MRI characteristics and pathology of intracranial neuron and mixed neuronal-glial tumor. Methods： Clinical data, histopathology and MRI findings in 26 patients with intracranial neuron and mixed neuronalglial tumor proved by pathology were analysed retrospectively. Results： Eleven dysembryoplasia neuroepithelial tumor（DNT）, mainly seen in the supratentorial brain and beneath cerebral cortex, some were seen as cystic masses, appearing as low signal intensity on T1WI and high signal intensity on T2WI. DNT had a well-demarcated and no or only slight edema, no enhancement or slight inhomogcous enhancement; 11 gangliogliomas mainly seen in the supratentorial brain appearing as low signal intensity on T1WI and high signal intensity on T2WI. Two showed mixed signal intensity, margin of lesion was well-demarcated and no edema or slight edema, no enhancement or slight uneven enhancement, 3 central neurocytomas, which were located in the lateral cerebral ventricle, all showed mixed signal intensity on T2WI and T2WI, with cystic components. Enhancement was inhomogeneous; 1 desmoplastie gangliogliomas seen as cystic masses, located in fronto-temporal-apical lobe, had septation, appearing as low signal intensity on T1WI and high signal intensity on TEWI. Conclusion： Intracranial neuronal and mixed ncuronal-glial tumours had no characteristic imaging features. It should be closely referred with clinical manifestations.