Ethanol Embolotherapy of Vascular Malformations: Clinical Outcomes at a Single Center |
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| Affiliation: | 1. Department of Radiology, Section of Nuclear Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North St Clair, Suite 800, Chicago, IL 60611;2. Section of Interventional Radiology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North St Clair, Suite 800, Chicago, IL 60611;1. Department of Radiology, University of California, Los Angeles, Los Angeles;2. Department of Radiology, University of California, San Diego, San Diego, California;3. Department of Radiology, University of Washington, Seattle, Washington;1. Department of Radiation Oncology, Emory University, 1365 Clifton Road NE, Suite CT 104, Atlanta, GA 30322;2. Department of Radiology and Imaging Sciences, Divisions of Interventional Radiology and Image Guided Medicine, Emory University, 1365 Clifton Road NE, Suite CT 104, Atlanta, GA 30322;3. Divisions of Nuclear Medicine and Molecular Imaging, Emory University, 1365 Clifton Road NE, Suite CT 104, Atlanta, GA 30322;4. Departments of Biostatistics and Bioinformatics, Emory University, 1365 Clifton Road NE, Suite CT 104, Atlanta, GA 30322;5. Winship Cancer Institute, Emory University, 1365 Clifton Road NE, Suite CT 104, Atlanta, GA 30322;1. Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, Rutgers Biomedical and Health Sciences, New Brunswick, NJ 08903-0019;2. Center for Biomedical Imaging & Informatics, Rutgers Cancer Institute of New Jersey, Rutgers Biomedical and Health Sciences, New Brunswick, NJ 08903-0019;3. Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers Biomedical and Health Sciences, New Brunswick, NJ 08903-0019;4. Department of Biostatistics, School of Public Health, Rutgers Biomedical and Health Sciences, New Brunswick, NJ 08903-0019;5. Department of Radiology, Rutgers Robert Wood Johnson Medical School, One Robert Wood Johnson Place MEB 404, PO Box 19, New Brunswick, NJ 08903-0019;1. Department of Microbiology, Biomedical Diagnostic Center (CDB), ISGlobal, Barcelona Center for International Health Research (CRESIB), Hospital Clínic, Universitat de Barcelona, Barcelona, Spain;2. Pfizer Inc., Collegeville, PA, USA |
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| Abstract: | PurposeTo retrospectively evaluate the results of endovascular therapy of vascular malformations principally treated with ethanol embolization at a single center.Materials and MethodsFrom May 1999 to December 2012, 46 patients (28 female, 18 male) with vascular malformations (31 venous malformations, 15 arteriovenous malformations [AVMs]) throughout the body (nine upper extremity, 31 lower extremity, and six truncal) who underwent ethanol embolization were studied and followed up. Demographic factors, clinical findings, imaging data, and patient-reported changes in symptoms were collected and analyzed. Follow-up data were obtained by office visits, repeat imaging, and telephone contact.ResultsTwenty-four patients (52.2%) were considered cured, 12 (26.1%) showed improvement, and 10 (21.7%) had no change or showed worsening. Similar rates of cure or improvement were seen for AVMs and venous malformations (P = 0.67). Lesion location, depth, and size were not associated with differences in outcomes (P = .87, P = .37, and P = .61, respectively). Type 1 and type 2 AVMs were cured more often than other AVM types. The overall complication rate was 24% (11 of 46 patients). Minor complications were seen in six individuals (13%), and major complications developed in five patients (11%).ConclusionsEthanol embolization of vascular malformations produces good outcomes, with control or relief of symptoms in a majority of patients. |
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| Keywords: | AVM" },{" #name" :" keyword" ," $" :{" id" :" key0010" }," $$" :[{" #name" :" text" ," _" :" arteriovenous malformation |
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