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Radiofrequency Ablation of Hepatic Cysts: Evaluation of Therapeutic Efficacy
Affiliation:1. Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104;2. Department of Interventional Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104;1. Section of Interventional Radiology and Department of Radiology, Memorial Sloan–Kettering Cancer Center, 1275 York Ave., Suite H 118, New York, NY 10065;2. Department of Epidemiology and Biostatistics, Memorial Sloan–Kettering Cancer Center, 1275 York Ave., Suite H 118, New York, NY 10065;3. Department of Medicine, Memorial Sloan–Kettering Cancer Center, 1275 York Ave., Suite H 118, New York, NY 10065;1. Department of Radiology, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201;2. Department of Medicine, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201;3. Department of Pathology, University of Maryland School of Medicine, 22 S. Greene St., Baltimore, MD 21201;1. Department of Radiology, Memorial Sloan–Kettering Cancer Center, 1275 York Ave., New York, NY 10065;2. San Diego Imaging, Sharp Memorial Hospital, San Diego, California;3. Department of Radiology, Centre Léon Bérard, Lyon, France
Abstract:
PurposeTo evaluate therapeutic efficacy of radiofrequency (RF) ablation for treatment of hepatic cysts with the use of a single cooled electrode after aspiration of the cyst contents.Materials and MethodsFourteen hepatic cysts (mean diameter, 7.8 cm; range, 3.7–12.7 cm) in 14 patients treated by RF ablation during a 3-year period were retrospectively reviewed. RF ablation was performed after aspiration of the cyst contents until a cyst measured no more 3 cm in diameter. The volumes of each cyst on computed tomography (CT) were measured before and after RF ablation, and volume reduction rates were calculated.ResultsFollow-up CT was performed a mean of 437 days after RF ablation (range, 32–1,326 d). One cyst was surgically removed because of regrowth. Nine had a volume reduction rate greater than 75%. Eight of nine cysts 8.5 cm in diameter or smaller markedly decreased in volume (mean reduction rate, 93.6%; range, 76.8%–100%). Cysts 8.5–12.0 cm in diameter (n = 4) showed a 61.7% reduction rate (range, 26.0%–98.8%). The mean volume reduction rate was 83.5% (range, 8.1%–100%) in the nine cysts with less than 10 mL of residual fluid after aspiration, compared with 43.2% in the five cysts with more than 10 mL of residual fluid. The volume reduction rate was 34.4% in septated cysts after aspiration, in contrast to 83.0% in nonseptated cysts. There were no major complications from RF ablation.ConclusionsRF ablation may be effective for the treatment of benign hepatic cysts and may be considered as an alternative to conventional sclerotherapy or surgery.
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