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CHD患者治疗前后血清IL-2、SOD和血浆ET-1检测的临床意义
引用本文:宋发达. CHD患者治疗前后血清IL-2、SOD和血浆ET-1检测的临床意义[J]. 放射免疫学杂志, 2010, 23(3): 263-264
作者姓名:宋发达
作者单位:连云港市第一人民医院东方医院,222042
摘    要:目的:探讨冠心病(CHD)患者治疗前后血清IL-2、SOD和血浆ET-1水平的变化和意义。方法:应用放射免疫分析对65例CHD患者进行了血清IL-2、SOD和血浆ET-1检测(其中稳定型心绞痛30例,不稳定型心绞痛22例,急性心肌梗死13例,并以35名正常健康人作比较。结果:CHD患者在治疗前血清IL-2、SOD水平非常显著地低于正常人组(P〈0.01),而血浆ET-1水平又非常显著地高于正常人组(P〈0.01)。经中西医结合治疗3个月后与正常人组比较无显著性差异(P〉0.05)。结论:血清IL-2、SOD和血浆ET-1水平的变化参与了CHD的发生与发展。

关 键 词:冠心病  白细胞介素-2  稳定型心绞痛  不稳定型心绞痛  急性心肌梗死  超氧化物岐化酶  内皮素-1

Clinical Significance of the Changes of Serum IL-2, SOD and Plasma ET-1Levels After Treatment in Patients with Coronary Heart Diseases
Song Fa-da. Clinical Significance of the Changes of Serum IL-2, SOD and Plasma ET-1Levels After Treatment in Patients with Coronary Heart Diseases[J]. Journal of Radioimmanology, 2010, 23(3): 263-264
Authors:Song Fa-da
Affiliation:Song Fa-da Lianyungang First People's Hospital East Hospital,Lianyungang(222042),China
Abstract:Objective To study the changes of serum IL-2,SOD and plasma ET-1 levels after treatment in patients with coronary heart diseases.Methods Serum IL-2,SOD and plasma ET-1 levels were detected with RIA in 65 patients with coronary heart diseases(30SAP,22UAP,13AMI)and 35 controls.Results Before treatment,serum IL-2,SOD levels in CHD patients were significantly lower than those in controls(P<0.01),while the plasma ET-1 levels in CHD patients were significantly higher than those in controls(P<0.01).After treatment...
Keywords:coronary heart diseases(CHD)  interleukin-2(IL-2)  stable angina pectoris(SAP)  unstable angina pectoris(UAP)  acute myocardial infaretion(AMI)  superoxide dismutase(SOD)  endothelin-1(ET-1)  
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