高脂血症性急性胰腺炎临床特点分析

目的分析高脂血症性胰腺炎的临床特点。方法回顾性分析2009年9月-2012年9月收治的50例高脂血症性急性胰腺炎(HLAP)患者的临床资料,并与同期收治的211例胆源性胰腺炎(BAP)患者进行比较。收集患者性别、年龄、住院天数;住院时血甘油三酯(TG)、血胆固醇(TC)、血糖、血钙、血淀粉酶、尿淀粉酶、脂肪肝发生率及复发率情况。结果 HLAP组患者年龄偏小,男性多于女性,甘油三酯、血糖、脂肪肝、复发率明显高于BAP组,血淀粉酶、尿淀粉酶明显低于BAP组,胆固醇、血钙平均住院天数两组未见明显差异。结论高脂血症性急性胰腺炎和甘油三酯关系密切,好发于中青年男性,发病率逐年增加,易并发糖尿病和脂肪肝,不伴有血、尿淀粉酶的显著升高,且易复发,积极降血脂治疗有利于控制病情,并防止复发。

Analysis of clinical characteristics of hyperlipidemic pancreatitis

Objective To investigate the clinical characteristics of hyperlipidemic pancreatitis. Methods A retrospective controlled study on 50 cases of hyperlipidemic acute pancreatitis （HLAP） from September,2009 to September,2012, and the 211 cases of biliogenic pancreatitis in same period were chosen as control group. Clinical variables included age, sex, hospitalization time, hospi- tal blood triglyceride（TG）, blood cholesterol （TC）, blood glucose, blood calcium, blood amylase, urine amylase and the incidence of fatty liver and the recurrence rate. Results Compared with the control group, the blood amylase and urine amylase of patients with HLAP were significantly lower,while serum triglycerides, blood glucose, fatty liver and the recurrence rate were obviously higher. Cho- lesterol, blood calcium, average hospitalization days in the two groups did not see obvious difference. Conclusion Hyperlipidemia pan- creatitis is closely related to triglycerides, used to appear mostly in young and middle-aged men, incidence increased year by year, eas- ily complicated by diabetes and fatty liver, not accompanied by a significant rise in blood and urine amylase, and easy to relapse, the Treatment of lower cholesterol is beneficial to control the disease and prevent recurrence.