心理训练对心理应激后陆军特种兵血清蛋白质谱特征的影响

目的观察采取不同方式进行心理训练后,陆军特种兵心理应激时血清蛋白质谱的变化特点,以评价心理训练效果。方法将96名特种兵新兵随机均分为单纯心理训练组、循环心理训练组和对照组(n=32),训练4周后,参加高强度模拟防暴演习。采用表面增强激光解吸电离飞行时间质谱(SELDI-TOF-MS)技术结合蛋白质芯片检测各组血清蛋白表达谱的变化。结果方差分析结果显示,3组血清中质荷比(M/Z)为6417.89、134.21、5 171.91、4 972.7Da的4种蛋白相对含量差异显著(P<0.05);与对照组比较,单纯心理训练组M/Z为9134.21、5 171.9Da的2种蛋白表达显著升高(P<0.05),而循环心理训练组4种蛋白的表达均显著升高(P<0.05);与单纯心理训练组比较,循环心理训练组M/Z为6417.81、4 972.7Da的2种蛋白表达显著升高(P<0.05)。M/Z为6417.8和14 972.7Da的蛋白组成的分类树模型在学习模式及测试模式下可将96名战士完全正确分组。结论心理训练可使应激后低表达的蛋白明显上调,提高机体对心理应激的适应能力,且循环心理训练的效果优于单纯心理训练。

Effects of psychological training on the serum protein expression in soldiers under mental stress

Objective To investigate the changes of serum protein expression in soldiers under mental stress,who have undergone different psychological trainings,and to evaluate the effect of the psychological training.Methods Ninety-six male commando soldiers were randomly assigned into the common psychological training group,the circulation psychological training group,and the control group(each group comprising 32 soldiers).After four weeks of training,the soldiers in the three groups attended a high-intensity simul...